USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: P68371 USC-OGP 2-DE database:  P68371 P68371 General information about the entry View entry in simple text format Entry name TBB4B_HUMAN Primary accession number P68371 Secondary accession number(s) P05217 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Tubulin beta-4B chain; AltName: Full=Tubulin beta-2 chain; AltName: Full=Tubulin beta-2C chain;. Gene name Name=TUBB4B Synonyms=TUBB2C Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0067: pI=4.86; Mw=51629 SPOT OGP-0068: pI=4.95; Mw=51402 SPOT OGP-0176: pI=4.81; Mw=27222 PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0369: pI=5.00; Mw=49250 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0671: pI=5.02; Mw=50928 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1160: pI=5.05; Mw=49904 SPOT OGP-1210: pI=5.74; Mw=37929 Cross-references UniProtKB/Swiss-Prot P68371; TBB4B_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name TBB4B_HUMAN Primary accession number P68371 Secondary accession number(s) A2BFA2 P05217 Sequence was last modified on  August 13, 1987 (version 1) Annotations were last modified on  March 15, 2017 (version 138) Name and origin of the protein Description RecName: Full=Tubulin beta-4B chain; AltName: Full=Tubulin beta-2 chain; AltName: Full=Tubulin beta-2C chain; Gene name Name=TUBB4B Synonyms=TUBB2C Encoded on Name=TUBB4B; Synonyms=TUBB2C Keywords Acetylation; Complete proteome; Cytoplasm; Cytoskeleton; GTP-binding; Isopeptide bond; Microtubule; Nucleotide-binding; Phosphoprotein; Reference proteome. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL X02344; CAA26203.1; -; Genomic_DNA EMBL BX255925; CAM24148.1; -; Genomic_DNA EMBL BC001911; AAH01911.1; -; mRNA EMBL BC002783; AAH02783.1; -; mRNA EMBL BC002885; AAH02885.1; -; mRNA EMBL BC004188; AAH04188.1; -; mRNA EMBL BC007889; AAH07889.1; -; mRNA EMBL BC012835; AAH12835.1; -; mRNA EMBL BC019359; AAH19359.1; -; mRNA EMBL BC019829; AAH19829.1; -; mRNA EMBL BC039175; AAH39175.1; -; mRNA EMBL BC071889; AAH71889.1; -; mRNA CCDS CCDS7039.1; -; . PIR I38370; I38370; . RefSeq NP_006079.1; NM_006088.5; . UniGene Hs.433615; -; . ProteinModelPortal P68371; -; . SMR P68371; -; . BioGrid 115656; 143; . IntAct P68371; 61; . MINT MINT-1390314; -; . STRING 9606.ENSP00000341289; -; . ChEMBL CHEMBL1848; -; . DrugBank DB00518; Albendazole; . DrugBank DB05147; CYT997; . DrugBank DB03010; Epothilone B; . DrugBank DB01873; Epothilone D; . DrugBank DB00643; Mebendazole; . DrugBank DB04910; Oxibendazole; . iPTMnet P68371; -; . PhosphoSitePlus P68371; -; . SwissPalm P68371; -; . BioMuta TUBB4B; -; . DMDM 55977480; -; . OGP P05217; -; . REPRODUCTION-2DPAGE IPI00007752; -; . SWISS-2DPAGE P68371; -; . EPD P68371; -; . MaxQB P68371; -; . PaxDb P68371; -; . PeptideAtlas P68371; -; . PRIDE P68371; -; . TopDownProteomics P68371; -; . DNASU 10383; -; . Ensembl ENST00000340384; ENSP00000341289; ENSG00000188229; . GeneID 10383; -; . KEGG hsa:10383; -; . UCSC uc004cmh.2; human; . CTD 10383; -; . DisGeNET 10383; -; . GeneCards TUBB4B; -; . HGNC HGNC:20771; TUBB4B; . HPA CAB010880; -; . HPA HPA043640; -; . HPA HPA046280; -; . MIM 602660; gene; . neXtProt NX_P68371; -; . OpenTargets ENSG00000188229; -; . PharmGKB PA142670672; -; . eggNOG KOG1375; Eukaryota; . eggNOG COG5023; LUCA; . GeneTree ENSGT00760000119061; -; . HOGENOM HOG000165710; -; . HOVERGEN HBG000089; -; . InParanoid P68371; -; . KO K07375; -; . OMA FWEVIND; -; . OrthoDB EOG091G06U2; -; . PhylomeDB P68371; -; . TreeFam TF300298; -; . Reactome R-HSA-1445148; Translocation of GLUT4 to the plasma membrane; . Reactome R-HSA-190840; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; . Reactome R-HSA-190861; Gap junction assembly; . Reactome R-HSA-2132295; MHC class II antigen presentation; . Reactome R-HSA-2467813; Separation of Sister Chromatids; . Reactome R-HSA-2500257; Resolution of Sister Chromatid Cohesion; . Reactome R-HSA-2565942; Regulation of PLK1 Activity at G2/M Transition; . Reactome R-HSA-380259; Loss of Nlp from mitotic centrosomes; . Reactome R-HSA-380270; Recruitment of mitotic centrosome proteins and complexes; . Reactome R-HSA-380284; Loss of proteins required for interphase microtubule organization from the centrosome; . Reactome R-HSA-380320; Recruitment of NuMA to mitotic centrosomes; . Reactome R-HSA-389957; Prefoldin mediated transfer of substrate to CCT/TriC; . Reactome R-HSA-389960; Formation of tubulin folding intermediates by CCT/TriC; . Reactome R-HSA-389977; Post-chaperonin tubulin folding pathway; . Reactome R-HSA-437239; Recycling pathway of L1; . Reactome R-HSA-5610787; Hedgehog 'off' state; . Reactome R-HSA-5617833; Cilium Assembly; . Reactome R-HSA-5620912; Anchoring of the basal body to the plasma membrane; . Reactome R-HSA-5620924; Intraflagellar transport; . Reactome R-HSA-5626467; RHO GTPases activate IQGAPs; . Reactome R-HSA-5663220; RHO GTPases Activate Formins; . Reactome R-HSA-6798695; Neutrophil degranulation; . Reactome R-HSA-6807878; COPI-mediated anterograde transport; . Reactome R-HSA-6811434; COPI-dependent Golgi-to-ER retrograde traffic; . Reactome R-HSA-6811436; COPI-independent Golgi-to-ER retrograde traffic; . Reactome R-HSA-68877; Mitotic Prometaphase; . Reactome R-HSA-8852276; The role of GTSE1 in G2/M progression after G2 checkpoint; . Reactome R-HSA-8854518; AURKA Activation by TPX2; . Reactome R-HSA-983189; Kinesins; . SIGNOR P68371; -; . ChiTaRS TUBB4B; human; . GeneWiki TUBB2C; -; . GenomeRNAi 10383; -; . PRO PR:P68371; -; . Proteomes UP000005640; Chromosome 9; . Bgee ENSG00000188229; -; . CleanEx HS_TUBB2C; -; . Genevisible P68371; HS; . GO GO:0035578; C:azurophil granule lumen; TAS:Reactome; . GO GO:0005856; C:cytoskeleton; TAS:ProtInc; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0031012; C:extracellular matrix; IDA:BHF-UCL; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:1903561; C:extracellular vesicle; IDA:UniProtKB; . GO GO:0005874; C:microtubule; IDA:UniProtKB; . GO GO:0015630; C:microtubule cytoskeleton; IDA:HPA; . GO GO:0043209; C:myelin sheath; IEA:Ensembl; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0003725; F:double-stranded RNA binding; IDA:MGI; . GO GO:0005525; F:GTP binding; IEA:UniProtKB-KW; . GO GO:0003924; F:GTPase activity; IEA:InterPro; . GO GO:0042288; F:MHC class I protein binding; TAS:UniProtKB; . GO GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro; . GO GO:0051082; F:unfolded protein binding; NAS:UniProtKB; . GO GO:0097711; P:ciliary basal body docking; TAS:Reactome; . GO GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome; . GO GO:0007017; P:microtubule-based process; IEA:InterPro; . GO GO:0006928; P:movement of cell or subcellular component; TAS:ProtInc; . GO GO:0042267; P:natural killer cell mediated cytotoxicity; NAS:UniProtKB; . GO GO:0043312; P:neutrophil degranulation; TAS:Reactome; . Gene3D 1.10.287.600; -; 1; . Gene3D 3.30.1330.20; -; 1; . Gene3D 3.40.50.1440; -; 1; . InterPro IPR013838; Beta-tubulin_BS; . InterPro IPR002453; Beta_tubulin; . InterPro IPR008280; Tub_FtsZ_C; . InterPro IPR000217; Tubulin; . InterPro IPR018316; Tubulin/FtsZ_2-layer-sand-dom; . InterPro IPR023123; Tubulin_C; . InterPro IPR017975; Tubulin_CS; . InterPro IPR003008; Tubulin_FtsZ_GTPase; . PANTHER PTHR11588; PTHR11588; 1; . Pfam PF00091; Tubulin; 1; . Pfam PF03953; Tubulin_C; 1; . PRINTS PR01163; BETATUBULIN; . PRINTS PR01161; TUBULIN; . SMART SM00864; Tubulin; 1; . SMART SM00865; Tubulin_C; 1; . SUPFAM SSF52490; SSF52490; 1; . SUPFAM SSF55307; SSF55307; 1; . PROSITE PS00227; TUBULIN; 1; . PROSITE PS00228; TUBULIN_B_AUTOREG; 1; .

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